Téma: Overview works

Treatment of arterial hypertension in chronic kidney disease

Peter Ponťuch

Arterial hypertension occurs in 50-75 % patients with chronic kidney disease and is an important risk factor for progression of cardiovascular and kidney diseases. The new K/DOQI guidelines summarize the results of large trials on the treatment of hypertension, cardiovascular and kidney diseases. The target blood pressure in nondiabetic and diabetic kidney diseases should be <130/80 mmHg. Hypertensive, and even normotensive patients with microalbuminuria or mild proteinuria should be treated with angiotensin converting enzyme inhibitors or angiotensin receptor blockers. Patients with chronic kidney diseases are at high cardiovascular risk, which doubles with each increment of systolic blood pressure of 20 mmHg or diastolic blood pressure of 10 mmHg above blood pressure of 115/75 mmHg. Long-term efficient antihypertensive therapy has a beneficial effect to reduce the risk of cardiovascular disease or slow the progression of kidney disease.

Ročník 2004  Témy časopisu Internal medicine 9 / 2004

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prof. MUDr. Ivica Lazúrová, CSc. FRCP

REPRESENTATIVE OF CHAIRMAN
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MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Viera Fábryová, CSc.
MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
prof. MUDr. Štefan Hrušovský, CSc. Dr.SVS.
prof. MUDr. Rudolf Hyrdel, CSc.
doc. MUDr. Oľga Jurkovičová, CSc.
doc. MUDr. Zdenko Killinger, PhD.
doc. MUDr. Soňa Kiňová, PhD.
prof. MUDr. Peter Mitro, PhD.
doc. MUDr. Viliam Mojto, CSc., MHA
prof. MUDr. Karel Pacák, DrSc.
prof. MUDr. Juraj Payer, CSc., FRCP
doc. MUDr. Ján Podoba, CSc.
prof. MUDr. Igor Riečanský, DrSc.
doc. MUDr. Ján Staško, PhD.
doc. MUDr. Mária Szántová, PhD.
prof. MUDr. Ivan Tkáč, PhD.

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1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett ́ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.

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c. propionibacterium acnes
d. endothelial growth factor


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