Milan Nikš, Dušan Krkoška, Juraj Hanzen a Richard Ostertág
Antibiotic resistance became a global threat. Analysis of reasons leading to the critical situation has confirmed that only a prudent antibiotic use can slow down the spread of resistance. Careful evaluation of local resistance situation and a good knowledge of underlying resistance mechanisms is a prerequisite for rational antibiotic prescribing. The most significant antibiotic resistance mechanisms are discussed here. However, the article cannot provide the complete overview of the antibiotic resistance in the Slovak Republic. Short information invites antibiotic prescribers to visit the Slovak National Resistance Surveillance database on internet (http//www.snars.sk), containing actual antibiotic susceptibility surveillance data.