Juraj Hrnčiar
For an experienced physician is determining of free thyroxin – FT4 and TSH IMA by a sensitive method of 3rd generation and evaluating of their mutual and reciprocal relation crucial for confirming functional disorders of thyroid gland. Determination of autoantibodies against thyroid peroxidase (TPO-Ab), against thyreoglobuline (TgAb) and TSH-receptors (TRAb), as well as routine thin needle biopsy of thyroid gland under ultrasound control with cytological evaluation of the sample (diagnostics of thyreoiditis and carcinomas) has an irreplaceable significance for confirming of etiopathogenesis of thyreopathies. Development of new thyroidal tests has narrowed the field of activity and significance of former radioisotope examinations as accumulation test and gamagraphy of thyroid gland. Accumulation test has been currently used only for calculation of therapeutic dose of radioiodine and thyroid gland gamagraphy has been replaced by ultrasonography which is cost effective, more available, testifying and without any radiation load.