Michal Demeter, Janka Božíková, Peter Bánovčin, Rudolf Hyrdel
Irritable bowel syndrome (IBS) is frequent GI functional disorder. It’s prevalence is approximately 20 % (20 000/100 000)(1). Etiopathogenesis IBS depends on many exogenous (diet, chronic stress, physical and sexual abuse) and endogenous (psychiatric disorders, colonic flora, visceral hypersensitivity) factors. IBS presents with flatulence, bloating and abdominal pain, that are relieved after defecation. There are changes of stools frequency and consistency in typical cases. Diagnosis of IBS is based on symptoms analysis (Manning and Rome III criteria). Divergent clinical presentation and possible missing of serious organic illness is the basic problem of IBS diagnosis. IBS therapy is complex. It is based on lifestyle modification (stress copying policy), psychotherapy and longtime reassurance about benigne character of illness. Drug therapy helps to relieve symptoms at the CNS (antidepressants, psychiatric medication) as well as bowel (spasmolytics, prokinetics, serotonergic drugs) levels.