Téma: Overview works

Prevention and treatment of kidney damage in diabetic patients

Peter Ponťuch

Prevalence of diabetic nephropathy after 20 years of type 1 diabetes duration amounts for 30 - 40 %. We found in type 2 diabetic patients the prevalence of microalbuminuria 23 % and clinical proteinuria 11 %. Early screening of microalbuminuria (30 - 300 mg/24 h), the first manifestation of diabetic kidney damage, is an important tool in the prevention of diabetic nephropathy. Optimal glycaemic control is effective mainly in incipient and overt nephropathy without severe reduction in glomerular filtration rate. The goal of antihypertensive therapy is to decrease blood pressure below 130/80 mmHg. In the treatment of diabetic nephropathy with microalbuminuria or clinical albuminuria, angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) should be used, with the exception of pregnant diabetic patient or drug intolerance.

Ročník 2009  Témy časopisu Internal medicine 4 / 2009

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prof. MUDr. Ivica Lazúrová, CSc. FRCP

REPRESENTATIVE OF CHAIRMAN
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MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
prof. MUDr. Štefan Hrušovský, CSc. Dr.SVS.
prof. MUDr. Rudolf Hyrdel, CSc.
doc. MUDr. Oľga Jurkovičová, CSc.
doc. MUDr. Zdenko Killinger, PhD.
doc. MUDr. Soňa Kiňová, PhD.
prof. MUDr. Peter Mitro, PhD.
doc. MUDr. Viliam Mojto, CSc., MHA
prof. MUDr. Karel Pacák, DrSc.
prof. MUDr. Juraj Payer, CSc., FRCP
doc. MUDr. Ján Podoba, CSc.
prof. MUDr. Igor Riečanský, DrSc.
doc. MUDr. Ján Staško, PhD.
doc. MUDr. Mária Szántová, PhD.
prof. MUDr. Ivan Tkáč, PhD.

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1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett ́ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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d. endothelial growth factor


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