Téma:  Case Studies

Significance of coeliac disease as a precancerosis of t-lymfoma associated with enteropathy in geriatric patients – case report

Peter Kružliak, Eva Čičmancová

Non-Hodgkin’s T-lymfoma associated with enteropathy (EATL) is a tumor of cells corresponding with intraepithelial lymphocytes of T- cells line of the small intestine with heterogeneity of morphological picture and clinical course mostly depending on the grade of blastic transformation of tumor cells. It occurs mainly in relation with malabsorption syndrome mostly with sprue (coeliac disease) that is considered precancerosis of this tumor disease. Risk factors of development of this malignant complication in patients with sprue imply time of gluten exposition, coeliac disease diagnosed at higher age and coeliac disease refracter to therapy. It is a very severe disease with bad prognosis and high mortality. The authors present a clinical case of a female patient with a late diagnosed celiac disease at higher age that was complicated with development of EATL.

Ročník 2009  Témy časopisu Internal medicine 11 / 2009

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MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
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prof. MUDr. Peter Mitro, PhD.
doc. MUDr. Viliam Mojto, CSc., MHA
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prof. MUDr. Juraj Payer, CSc., FRCP
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prof. MUDr. Igor Riečanský, DrSc.
doc. MUDr. Ján Staško, PhD.
doc. MUDr. Mária Szántová, PhD.
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3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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