Eva Kolesárová, Martin Janičko, Ivana Valočíková, Matej Kolesár, Alžbeta Petrovová
Introduction: Nowadays obesity is considered to be one of the main risk factors of cardiovascular and cardiometabolic diseases. Determination of waist-to-height ratio is one of the possibilities how to establish central obesity. Present preventive strategies increasingly focus on an early detection of atherosclerosis indicators, where microalbuminuria also belongs. Aim: In our work we assessed indicators of abdominal obesity BMI, waist-to-height ratio and its relation to microalbuminuria. Group and method: The performed cross-sectional observation study in the group of 242 patients treated in the internal and nephrologic surgery for arterial hypertension, with/without complications, as diabetes mellitus type 2 and chronic kidney disease. In all patients we monitored waist, calculated BMI, ratio waist-to-height, 10 year risk of a fatal cardiovascular event according to the system SCORE, microalbuminuria, creatinine values, values of glomerular filtration and of lipid profile. Results: In our cohort, the waist-to-height ratio was related to microalbuminuria which was detected by albumin-creatinine ratio, namely in patients without diagnosis of chronic kidney diseases. In these patients we observed, in the group with microalbuminuria, distinctly higher values of waist-to-height ratio (median 0.61 [0.094] vs 0.69 [0.163]), p = 0.001. Similar results we found out also for BMI (median 29.1 [7.66] vs. 32.4 [10.8], p = 0.021). Neither in the whole cohort nor in any subgroup had we found any distinct relation waist-to-height ratio with 10 year risk of fatal CV event according to SCORE. Conclusion: In the submitted study we found out that waist-to-height ratio in the population of patients without chronic kidney disease ration might serve as an indicator of microalbuminuria and in figurative sense also of cardiological risk. It seems that waist-to-height ratio might be an important screening tool of cardiovascular risk, comparable with BMI.