Ivica Lazúrová
Adrenal incidentalomas or clinically inapparent adrenal mass are considered as one of the most frequent tumours in human pathology. More frequently they appear in women, in elderly, in patients with metabolic syndrome and in patients with malignant diseases. In their management the basic task of an endocrinologist and physician is exclusion of hormonal activity and differentiation of a malignant lesion from a benign one. At present there is not a uniform consensus related to the management of adrenal incidentalomas. The most frequent cause of hyperfunction is subclinical hypercortisolism whose clinical importance is still unclear and so also therapeutical approach to these patients is controversial. Recommendations for the frequency of radiological imaging at monitoring of patients with incidentalomas of adrenal glands are also not clear. Recently it seems that present recommendations were not rational enough and increased the risk of false positivity of hormonal examinations. What is more, repeated CT examinations exposing the patient to ionizing radiation might have the risk of cancer development minimum such as the risk of malignant degeneration of adrenal incidentaloma itself.