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Časopis Internal medicine – Článok Efficacy of tilt training and its effect on baroreflex sensitivity in patients with recurrent vasovagal syncope

Internal medicine

Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné
Téma: ORIGINAL WORKS

Efficacy of tilt training and its effect on baroreflex sensitivity in patients with recurrent vasovagal syncope

Miloš Šimurda, Peter Mitro, Ervín Müller

Aims: The mechanism of the beneficial effect of tilt training in the prevention of recurrence of vasovagal syncope is unclear.
The aim of the work was to investigate the clinical effect of tilt training and describe its effect on baroreflex sensitivity
in patients with recurrent vasovagal syncope.
Study population and methods: The study included 35 patients with recurrent vasovagal syncope and positive head-up
tilt test who remained symptomatic despite an increased intake of fluids and salt. 15 patients were lost during follow
-up, 4 patients were excluded from the study for lack of compliance with tilt training. 16 patients (6 men / 10 women)
with a mean age of 38.38 ± 15.2 years performed home tilt training for 6 months and recorded all presyncopal and syncopal
recurrences. Baroreflex sensitivity was assessed by the non-invasive continuous blood pressure measurement
for 5 minutes during controlled breathing. The baroreflex sensitivity measurements were performed before and after
tilt training.
Results: The recurrence of syncope occurred in 2 patients, 12 patients had recurrence of presyncope. The total number of
syncope and presyncope episodes after tilt training was significantly reduced (2.63 ± 2.03 episodes/year vs. 0.125 ± 0.34
episodes/year, p < 0.0001; 10.02 ± 7.69 episodes/year vs. 2.81 ± 3.85 episodes/year, p = 0.0081, respectively). There was
no significant effect of tilt training on baroreflex sensitivity (supine position: 15,19±12,51 ms/mmHg vs. 15,05 ± 8,48
ms/mmHg, p = 0,48; sitting position: 9,79 ± 3,75 ms/mmHg vs. 10,51 ± 4,72 ms/mmHg, p = 0,32; upright position: 6,29
± 2,05 ms/mmHg vs. 6,65 ± 2,33 ms/mmHg, p = 0,35).
Conclusion: Tilt training performed once daily for 6 months significantly reduced the number of syncopal and presyncopal
episodes in patients with vasovagal syncope. Compliance to tilt training was relatively low. Effect of tilt training on
baroreflex sensitivity was not observed, suggesting a different mechanism of positive effect of this training.

vasovagal syncope, tilt training, clinical effect, baroreflex sensitivity
Interná med. 2016; 16 (6): 241-245

Ročník 2016  Témy časopisu Internal medicine 6 / 2016

ORIGINAL WORKS

Miloš Šimurda, Peter Mitro, Ervín Müller

PREHĽADOVÉ PRÁCE

Peter Bánovčin, Martin Ďuríček, Michal Demeter, Zuzana Havlíčeková, Rudolf Hyrdel
Milan Nikš
Ján Murín, Miroslav Pernický, Romana Compagnon, Michaela Macháčová
Veronika Vargová, Mária Urdová
Zoltán Borbély, Andrea Mazanová, Miroslava Habarová
Jarmila Kucharská, Anna Gvozdjáková
Nie sú dostupné žiadne voľne dostupné články
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REPRESENTATIVE OF CHAIRMAN
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MEMBERS OF THE EDITORIAL BOARD
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MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
prof. MUDr. Štefan Hrušovský, CSc. Dr.SVS.
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doc. MUDr. Oľga Jurkovičová, CSc.
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doc. MUDr. Soňa Kiňová, PhD.
prof. MUDr. Peter Mitro, PhD.
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Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné