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Časopis Internal medicine – Článok Hepatotoxicity induced with herbal medicine and dietetic supplements

Internal medicine

Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné
Téma: Overview works

Hepatotoxicity induced with herbal medicine and dietetic supplements

Mária Szántová

Toxic liver injury induced with herbal medicine (HHT) involves toxicity mediated with the effect of herbal medicine or
dietetic supplements (HDS). In the recent years, its incidence is growing due to increasing share of over-the-counter
products of herbal medicine and dietetic supplements to reduce the weight or to form the figure. However, a significant
part of HHT stays undiagnosed and unrecognised. In comparison with medicaments, HHT is most frequently the cause
of acute liver failure. The article provides actual overview of epidemiological data, main risk factors, etiopathogenesis,
present diagnostic and differential and diagnostic approach. The female sex, overweight, obesity and excessive
consumption of alcohol are the most severe risk HHT factors. Updated RUCAM classification is a gold standard in HHT
diagnosis. The creation of multinational L/HHT net (medical and herbal hepatotoxicity) could help to improve the prognostic
outlook of patients and increase their detection, as they are significantly underdiagnosed.

herbal hepatotoxicity, dietary supplements, risk factors, diagnosis, RUCAM classification, DILIn
Interná med. 2017; 17 (12): 473-479

Ročník 2017  Témy časopisu Internal medicine 12 / 2017

Original works

Ivana Trojová, Miriam Kozárová, Zuzana Malachovská, Darina Petrášová, Ivana Paraničová, Ružena Tkáčová, Pavol Joppa

Overview works

Lucia Stančiaková, Miroslava Dobrotová, Jela Ivanková, Pavol Hollý, Peter Kubisz, Ján Staško
Mária Szántová
Daniela Ježová, Nataša Hlaváčová
Ján Lazúr
Dušan Holoubek, Gabriel Valočík, Ján Ignác, Monika Jankajová, Mariana Dvorožňáková, Peter Čandík
Jaroslava Brňová, Janka Prnová, Soňa Hnilicová, Lenka Micháliková
Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ivica Lazúrová, CSc. FRCP

REPRESENTATIVE OF CHAIRMAN
prof. MUDr. Juraj Payer, CSc., FRCP

MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Viera Fábryová, CSc.
MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
prof. MUDr. Štefan Hrušovský, CSc. Dr.SVS.
prof. MUDr. Rudolf Hyrdel, CSc.
doc. MUDr. Oľga Jurkovičová, CSc.
doc. MUDr. Zdenko Killinger, PhD.
doc. MUDr. Soňa Kiňová, PhD.
prof. MUDr. Peter Mitro, PhD.
doc. MUDr. Viliam Mojto, CSc., MHA
prof. MUDr. Karel Pacák, DrSc.
prof. MUDr. Juraj Payer, CSc., FRCP
doc. MUDr. Ján Podoba, CSc.
prof. MUDr. Igor Riečanský, DrSc.
doc. MUDr. Ján Staško, PhD.
doc. MUDr. Mária Szántová, PhD.
prof. MUDr. Ivan Tkáč, PhD.

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Eva Stachová
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1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett ́ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.

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c. propionibacterium acnes
d. endothelial growth factor


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Due to practical focus of the journal we would like to ask you to write the paper comprehensively, with emphasis on practical use of provided information in out-
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Send contributions in the e-mail to the address: stachova@amedi.sk
Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné