Janka Jakubíková, Ľubica Perďochová
Introduction: Incidence of acute otitis media is the most common in children under the 3 year of age. The cause of severe acute otitis media and its complications is increased worldwide spread of antibiotic resistance to S. pneumoniae. The efficient of method of prevention a many of pneumococcal acute otitis media is vaccination. Seven-valent pneumococcal vaccine (PCV 7) started to use in Slovakia on 2006 and in the year 2008 was vaccination recommended for children up to 2 year. On the end of 2008 were almost 70 % children less than two year of age vaccinated by this vaccine. From January 2009 a pneumococcal conjugate vaccine has been incorporate in obligatory childhood vaccination schedule. Material and Methods: In the present study are analyzed incidences of serotypes of S. pneumoniae in 32 children with severe acute otitis media hospitalized in Pediatric Otorinolaryngology Department in Bratislava after vaccination by Prevenar and effect of vaccine to incidence of AOM which required hospitalization. Results: The most common serotypes were 19A (28.13 %) and serotypes 3 (18.75 %) in both non-vaccinated and children-vaccinated with Prevenar. Serotypes 14, 6B, 9V, 6A, 1, 18C and 19C were found only in non-vaccinated children. The most difficult to treated were AOM due to full resistant serotype 19A. Conclusions: Effect of vaccination by conjugate pneumococcal vaccine Prevenar were with decreasing of number of hospitalized children suffering AOM in our department, and also emergence of resistant serotypes which are not in this vaccine. Extending more of serotypes in the vaccine will be useful for following decreasing of AOM due to S. pneumoniae. In Europe is at time of licensure vaccine against 13 serotypes of S. pneumoniae.