Miroslav Šašinka, Katarína Furková
Rhabdomyolysis (lysis of crossed stripped muscles) often leads to acute renal insufficiency that determines final diagnosis of a patient. The occurrence of rhabdomyolysis varies and it depends on environmental (earth quake, floods, etc.) and technological (car accidents, industrial disasters) factors. Occurrence of non-traumatic rhabdomyolysis in children has lately been rising the act linked with problems of pharmacotherapy in childhood but also with environmental factors (toxins, food change, etc.). The authors present detailed review of etiology and pathogenesis of rhabdomyolysis, practical and early diagnostics and modern standards of conservative (alkalization, osmostic and other diuretics, treatment of disorders of electrolyte balance) and elimination (hemodialysis, hemofiltratiom) therapy.