Veronika Hovancová1, Monika Maligec1, Kamila Trebuňová1, Milan Kuchta1, Eva Bálintová1, Marcel Zachar2, Ján Lepej3
In recent years pulmonary embolism or other serious thromboembolic diseases in children are still more often diagnosed due to more intensive use of invasive diagnostic and therapeutical procedures, but also due to improved diagnostics. In aetiology, inborn or acquired thrombophilic conditions play a role. Clinically pulmonary embolism manifests by palpitations and dyspnoea, but also by non-specific symptoms as e.g. pain in the chest. Thromboembolism manifests according a site in which it arose as e.g. headache, disorder of consciousness, quantitative or qualitative disorder of consciousness, haematuria, limb oedema and others. In paediatric practice pulmonary embolism is still not sufficiently taken into consideration. According our experience the number of these conditions is increasing. In presented case studies we point out to rather typical course of thromboembolism in children with inborn or acquired thrombophilia, we describe a diagnostic process and give a systemic overview of therapeutical possibilities. The important factor in the treatment is along with anticoagulation treatment also prevention of other thrombophilic conditions. On the basis of our experience with diagnostics and treatment of these conditions we point out to a multidisciplinary approach and cooperation in their diagnostics and treatment including nuclear medicine, genetics, haematology, pneumology and other branches.