Gabriela Straková, Andrea Demitrovičová, Alena Vasilenková, Ingrid Brucknerová
Vitamin D is essential mainly for healthy bones, it takes an important role during its mineralization. Sufficient concentrate
of vitamin D during pregnancy has important influence on fetus osseous metabolism. The main source of active
form is sunshine (85 %) and food intake (15 %). The insufficiency of vitamin D is connected to occurrence of premature
babies osteopenia and rickets.
In our thesis we studied concentration of overall vitamin D at the newborn serum (n = 61) hospitalised in Neonatology
clinic of intensive medicine LF UK and DFNsP from June 2013 to March 2015. We did blood collection in the period of
first 14 days of their life. Representation of genders (male/female) was 28 (45,9 %)/33 (54,1 %), an average birth weight
was 1 461 g (750 – 1 988g), average gestational age 31,6 (24 – 40) week. These figures are presented as average (min. –
max.). The concentrate of vitamin D in serum we examined by set of Vitamin D total by firm Roche on analyser Cobas
e 411 (electrochemiluminescence immunoassays).
The average concentrate of vitamin D at our patients was 17,3 (1 – 51,9) ng/ml.
The concentration of 29 – 21 ng/ml is defined as insufficiency, 20 – 10 ng/ml as deficiency, below 10 ng/ml as serious deficiency
of vitamin D.
In consideration of our relatively small tested group of patients for more objective findings we would need to extend
the tested group, get more patients and also the group of physiological newborns.