Peter Kunč, Jaroslav Fábry, Peter Ferenc, Monika Cvancigerová
Introduction: Pneumocystis jirovecii (PCJ) is an opportunistic microbe which is the cause of severe pneumocystis
pneumonia in predisposed immunocompromised children. The degree and severity of the infection reflects the
host’s immune system. Most reported cases are in children with malignancies, HIV-positive or during immunosuppression
after organ transplants.
Aim: The aim of our report is to analyze hospitalization cases with pneumocystis positivity in secondary immunocompromised
premature infants from a low-stimulus environment with recurrent prolonged respiratory infections.
Results: We have detected by PCR method 10 positive samples from laryngeal swab or gastric acid aspirate from 40
enrolled infants aged from 2 to 12 months (median 5 months).
Conclusion: After targeted medical intervention in sufficient length we could declare significant improvement of patient’s
clinical status, faster disappear of bronchoconstriction, improved nutritional status, and decreased necessity of
repeated hospitalizations in the children.