Téma: 

Preterm uterine activity – the cause of preterm labor

Ľubomír Divéky

In this review we discuss our current understanding of the cellular basis of uterine contractility, highlighting those areas requiring further study. It is clear that the basic processes of excitation-contraction coupling lie within the myometrial cell, and that these may be modified by agonists. In particular, the contribution of calcium homeostatic pathways to the control of human myometrial contractility during gestation will be discussed. Maturation of the hypothalamic-pituitary adrenal axis occurs prematurely in response to stimuli such as stress. This provides the stimulus to the onset of parturition. Another pathways are- release of endothelin production from uteroplacental vessels or- decidual activation and production of interleukin-1, tumour necrosis factor - α and epidermal growth factor- which enhance prostaglandin production in both the amnion and chorion, and also in the myometrium. A substantial increase of eicosanoids concentration in myometrial tissue is probably an important condition for the ultimate step of myometrial stimulation and the onset of labor.

Ročník 2004  Témy časopisu Gynecology for practice 1 / 2004

CHAIRMAN OF THE EDITORIAL BOARD
MUDr. Tibor Bielik PhD.

MEMBERS OF THE EDITORIAL BOARD
prof. MUDr. Miroslav Borovský, CSc.
prof. MUDr. Ján Danko, CSc.
prof. MUDr. Ľudovít Danihel, PhD.
doc. MUDr. Ivan Hollý, PhD.
MUDr. Ľudovít Janek st.
doc. MUDr. Miroslav Korbeľ, CSc.
prof. MUDr. Štefan Lukačín, PhD.
prof. MUDr. Miloš Mlynček, CSc.
MUDr. Zuzana Nižňanská, PhD.
doc. MUDr. Martin Redecha, PhD.

PROFESSIONAL EDITOR
doc. MUDr. Martin Redecha, PhD.

EDITOR-IN-CHIEF
Ing. Danica Paulenová
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SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum size is 8 pages (font size 12, line spacing 1.5) with maximum five pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with emphasis on its practical usage for gynaecologists.

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(also in English), introduction, case study, discussion, conclusion, bibliography.

DIAGNOSTIC AND THERAPEUTICAL ALGORITHMS
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FROM BORDERLINE OF GYNECOLOGY
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- distinguish precisely numbers 1, 0 and letters l, O
- use always parentheses ( )
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MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - concise content summary in the extent maximum 10 lines (only at overview papers, case studies and From borderline of gynaecology). Write in 1st or 3rd person singular or plural (unify according the type of an article).
3. Key words - in the extent of 3-6 (just at overview papers, From borderline of cardiology).
4. English translation: paper title, summary, key words (only at overview papers, From borderline of gynaecology and case studies)
5. Text
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6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses. Use maximum 20 citations.

Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages. If an author is one, two or three - it is necessary to state all. If there are more than three authors it is necessary to write first three and "et all",. If there are more than three authors it is necessary to write first three and "et all", in Slovak and Czech citations "a spol.".

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For primary dysmenorrhoea from laboratory results it is characteristic:
a. increase of lymphocytes in differential BP over 40 %
b. increase of C-reactive protein and FW in the blood
c. decrease of Hb level in the blood below 100 g/l
d. none of them are characteristic

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