Téma: Clinical pharmacology

Psychopharmacological agents in pregnanc

Viera Kristová, Martin Wawruch

Usage of psychotropic drugs in pregnancy represents not only medical but also ethical problem. From a reason that pregnant women may not be the objective for clinical studies, there exist insufficient evidence-based data about effects of these drugs on the fetus. The present paper offers available information from the literature about possible risks of most frequently used psychotropic drugs in pregnancy: antidepressants, anxiolytics, hypnotics and antipsychotic drugs. Classification of single drugs in relation to their risk according to FDA is introduced on the base of which the doctor obtains information about likely adverse effects on the fetus. Though most of drugs are relatively safe, there exists certain risk for the fetus which has to be known to doctor to inform the pregnant women about risk and benefit of the treatment.

Ročník 2006  Témy časopisu Gynecology for practice 3 / 2006

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FROM BORDERLINE OF GYNECOLOGY
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6. Bibliography
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Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

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For primary dysmenorrhoea from laboratory results it is characteristic:
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b. increase of C-reactive protein and FW in the blood
c. decrease of Hb level in the blood below 100 g/l
d. none of them are characteristic

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