Téma: 

Erythrocyte antigens and importance of anti-erythrocyte antibodies

Monika Drakulová, Libuša Ceizelová

Blood group erythrocyte antigens are hereditary structures, which can be recognized by another individual not having these antigens and thus induce immune response. Regarding this possibility of immunization erythrocyte antigens are clinically significant for allogeneic blood transfusions, but an analogical mechanism can cause the mother’s immunization during pregnancy. Apart from the knowledge of erythrocyte membranes and blood groups the erythrocyte immunology deals with knowledge of antibodies against erythrocyte as well. Not all irregular anti-erythrocyte antibodies are employed in pathogenesis of neonatal hemolytic disease. Theoretically any anti-erythrocyte antibodies of the IgG class can cause it. The most common cause of severe neonatal hemolytic disease is antibody anti-D (85 %), anti-K (10 %), anti-C (3.5 %) and anti-E.

Ročník 2008  Témy časopisu Gynecology for practice 4 / 2008

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Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

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