Téma: 

Prenatal genetic diagnostics in the year 2007 in slovakia

František Cisárik

The author analysed prenatal genetic diagnostics in the year 2007. The data were obtained from the departments and laboratories of clinical genetics in Slovakia. The results from the year 2007 were compared with the results of previous years. In 2007 prenatal genetic diagnostics was performed to 3 505 women accounting for 6.4 % of all pregnant women. Indications substantially changed within previous years. Positive prenatal biochemical screening indicated 57 % of cases and maternal age over 35 indicated 30 % of cases. The frequency of indications due to positive sonographic markers of a higher risk of chromosomal anomalies or detection of a morphological defect of the foetus increased to 4.3 %. The frequency of chromosomal anomalies in this group was the highest (16.5 %), whereas the mean frequency of all indications was 2.82 %. From 99 detected chromosomal anomalies we expect a serious phenotype expression in 68 % of them.

Ročník 2009  Témy časopisu Gynecology for practice 1 / 2009

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Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

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