Iveta Stenová, Peter Harbulák, Zuzana Behúňová, Gabriela Iľková, Iveta Konýčková, Marek Drábek
Hypogonadotropic hypogonadism (HH) characterizes a secondary failure of gonads functions in a deficient gonadotropin secretion. Pubertas tarda, primary (secondary) amenorrhoea and infertility are dominant in the clinical picture. The therapy of these conditions involves application of exogenous gonadotropins or pulsatile GnRH. A case report presents a successful sterility treatment in the patient with a diagnosed idiopathic form of hypogonadotropic hypogonadism with application of pulsatile GnRH after a previous failure of application of exogenous gonadotropins. This therapeutical modality represents a safe, well-tolerated and financially acceptable alternative of ovarian stimulation in such a group of patients.