Téma: Overview works

The role of endogenous lh in folliculogenesis and its position in ovarian stimulation

Peter Harbulák

According to the two-cell-two-gonadotrophin theory and the LH therapeutic window concept the role of endogenous LH in folliculogenesis and ovarian steroidogenesis is broadly accepted. Current discussions are aimed at necessity and benefit of exogenous LH administration during ovarian stimulation in IVF cycles. The number of opinions on the necessity of exogenous LH applications in certain groups of patients for achieving good stimulation response is increasing. Currently more types of commercial gonadotrophin preparations with different composition and various pharmacodynamics are available. Better knowledge of mechanism and dynamics of LH effect in folliculogenesis convey rational selective application of gonadotrophins with LH activity and thus enhances security and successfulness of treatment. Following discussion on threshold and ceiling LH levels has been proceeding to this day and in the future will definitely bring further new knowledge. All types of gonadotrophins and their combinations have their own role in ovarian stimulation. The choice of gonadothropins with LH activity, its dosage and the onset of administration should be balanced.

Ročník 2010  Témy časopisu Gynecology for practice 4 / 2010

CHAIRMAN OF THE EDITORIAL BOARD
MUDr. Tibor Bielik PhD.

MEMBERS OF THE EDITORIAL BOARD
prof. MUDr. Miroslav Borovský, CSc.
prof. MUDr. Ján Danko, CSc.
prof. MUDr. Ľudovít Danihel, PhD.
doc. MUDr. Ivan Hollý, PhD.
MUDr. Ľudovít Janek st.
doc. MUDr. Miroslav Korbeľ, CSc.
prof. MUDr. Štefan Lukačín, PhD.
prof. MUDr. Miloš Mlynček, CSc.
MUDr. Zuzana Nižňanská, PhD.
doc. MUDr. Martin Redecha, PhD.

PROFESSIONAL EDITOR
doc. MUDr. Martin Redecha, PhD.

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SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum size is 8 pages (font size 12, line spacing 1.5) with maximum five pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with emphasis on its practical usage for gynaecologists.

CASE STUDY
Maximum extent is 7 pages. Structuring: summary, key words
(also in English), introduction, case study, discussion, conclusion, bibliography.

DIAGNOSTIC AND THERAPEUTICAL ALGORITHMS
Diagnosis and therapy processed into tables and schemes, with minimum text, with emphasis to conciseness and clarity.

MISCELLANEOUS
Reaction to overview articles, news in the field of diagnostics, therapy, trial results (maximum 3 pages), reports from professional events, abstracts from scientific work published abroad, not older than 1 year. Maximum extent is 1 page. Write the title of the paper in Slovak/Czech, authors, workplace, then title of the paper in English with full citation.

FROM BORDERLINE OF GYNECOLOGY
Intersectional theme elaborated complexly, well-arranged, clear (extent up to 8 pages).


MANUSCRIPT ELABORATION

Write the paper on computer in any common text editor.
- write full length of lines (do not use ENTER at the end of a line)
- do not arrange text into columns
- do not do page make-up, put tables at the end of the paper
- distinguish precisely numbers 1, 0 and letters l, O
- use always parentheses ( )
- explain abbreviations always when first used


MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - concise content summary in the extent maximum 10 lines (only at overview papers, case studies and From borderline of gynaecology). Write in 1st or 3rd person singular or plural (unify according the type of an article).
3. Key words - in the extent of 3-6 (just at overview papers, From borderline of cardiology).
4. English translation: paper title, summary, key words (only at overview papers, From borderline of gynaecology and case studies)
5. Text
If you insert pictures into a document, send also their original files in "jpg" format, create graphs in Excel and send also their original files. If you send photo documentation via post office, please, send just high-class originals. Mark each original by a number, under which it is mentioned in the text. Write in 1st or 3rd person singular or plural (unify according the type of an article).
6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses. Use maximum 20 citations.

Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages. If an author is one, two or three - it is necessary to state all. If there are more than three authors it is necessary to write first three and "et all",. If there are more than three authors it is necessary to write first three and "et all", in Slovak and Czech citations "a spol.".

Due to publishing of autodidactic tests it is necessary to add 4 questions to your article and 4 answers with marking of one correct answer, e.g.:

For primary dysmenorrhoea from laboratory results it is characteristic:
a. increase of lymphocytes in differential BP over 40 %
b. increase of C-reactive protein and FW in the blood
c. decrease of Hb level in the blood below 100 g/l
d. none of them are characteristic

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Due to practical focus of the journal we would like to ask you to write the paper comprehensively, with emphasis on practical use of provided information in out-patient gynaecological practice.

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