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Časopis Gynecology for practice – Článok Prenatal diagnostics in pregnancy with elevated level of afp in the maternal serum

Gynecology for practice

Reviewed, postgraduate scietific medical journal.
Period 4x per year
1336-3425
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Gynecology for practice
Gynecology for practice
Reviewed, postgraduate scietific medical journal.
Period 4x per year
Téma: 

Prenatal diagnostics in pregnancy with elevated level of afp in the maternal serum

Marián Križko ml., Martin Gábor, Peter Papcun, Mikuláš Redecha

Detection of alpha-fetoprotein concentrations in the maternal serum is important additional information for the USG screening in gravidity, namely in searching for defects of the neural tube, front abdominal wall, in early diagnostics of teratomata, obstructions of the gastrointestinal tract and kidney pathology. With the increased level of alpha-fetoprotein in the maternal serum over 2,5-multiple of the median, the risk of structural deviation is increasing in the foetus. In the exclusion of the positivity of higher alpha-fetoprotein concentrations in the maternal serum and structural deviations in the foetus via USG examination, the detection of values in amniotic fluid comes into consideration. But the specificity with the regard of the possible risk of amniocentesis is relatively low. In pregnant women with the alpha-fetoprotein concentration in the maternal serum over 2,5 multiple of the median, without USG finding of the foetal structural deviations, the described occurrence of chromosome aberration in the foetus is approximately 1 % and twice higher compared to common population. In this group aberrations of sexual chromosomes are the most frequent. In the cases when neither the USG examination nor the examination of karyotype leads to explanation of high levels of AFP in the maternal serum, the adverse pregnancy development was observed with higher risk of premature labour, intrauterine foetal growth retardation, intrauterine death after 24 weeks of gestation, abnormal placentation, placental abruption and preeclampsia.

Gynekol. prax 2012; 10 (3): 114-121

Ročník 2012  Témy časopisu Gynecology for practice 3 / 2012

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CHAIRMAN OF THE EDITORIAL BOARD
MUDr. Tibor Bielik PhD.

MEMBERS OF THE EDITORIAL BOARD
prof. MUDr. Miroslav Borovský, CSc.
prof. MUDr. Ján Danko, CSc.
prof. MUDr. Ľudovít Danihel, PhD.
doc. MUDr. Ivan Hollý, PhD.
MUDr. Ľudovít Janek st.
doc. MUDr. Miroslav Korbeľ, CSc.
prof. MUDr. Štefan Lukačín, PhD.
prof. MUDr. Miloš Mlynček, CSc.
MUDr. Zuzana Nižňanská, PhD.
doc. MUDr. Martin Redecha, PhD.

PROFESSIONAL EDITOR
doc. MUDr. Martin Redecha, PhD.

EDITOR-IN-CHIEF
Ing. Danica Paulenová
e-mail: paulenova@amedi.sk

GRAPHIC LAYOUT AND TYPESETTING
Lucia Vecseiová
e-mail: dtp@amedi.sk

MARKETING MANAGER
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LANGUAGE PROOFREADING
Mgr. Eva Doktorová

PROOFREADING OF ENGLISH TEXTS
Mgr. Jana Bábelová
SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum size is 8 pages (font size 12, line spacing 1.5) with maximum five pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with emphasis on its practical usage for gynaecologists.

CASE STUDY
Maximum extent is 7 pages. Structuring: summary, key words
(also in English), introduction, case study, discussion, conclusion, bibliography.

DIAGNOSTIC AND THERAPEUTICAL ALGORITHMS
Diagnosis and therapy processed into tables and schemes, with minimum text, with emphasis to conciseness and clarity.

MISCELLANEOUS
Reaction to overview articles, news in the field of diagnostics, therapy, trial results (maximum 3 pages), reports from professional events, abstracts from scientific work published abroad, not older than 1 year. Maximum extent is 1 page. Write the title of the paper in Slovak/Czech, authors, workplace, then title of the paper in English with full citation.

FROM BORDERLINE OF GYNECOLOGY
Intersectional theme elaborated complexly, well-arranged, clear (extent up to 8 pages).


MANUSCRIPT ELABORATION

Write the paper on computer in any common text editor.
- write full length of lines (do not use ENTER at the end of a line)
- do not arrange text into columns
- do not do page make-up, put tables at the end of the paper
- distinguish precisely numbers 1, 0 and letters l, O
- use always parentheses ( )
- explain abbreviations always when first used


MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - concise content summary in the extent maximum 10 lines (only at overview papers, case studies and From borderline of gynaecology). Write in 1st or 3rd person singular or plural (unify according the type of an article).
3. Key words - in the extent of 3-6 (just at overview papers, From borderline of cardiology).
4. English translation: paper title, summary, key words (only at overview papers, From borderline of gynaecology and case studies)
5. Text
If you insert pictures into a document, send also their original files in "jpg" format, create graphs in Excel and send also their original files. If you send photo documentation via post office, please, send just high-class originals. Mark each original by a number, under which it is mentioned in the text. Write in 1st or 3rd person singular or plural (unify according the type of an article).
6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses. Use maximum 20 citations.

Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages. If an author is one, two or three - it is necessary to state all. If there are more than three authors it is necessary to write first three and "et all",. If there are more than three authors it is necessary to write first three and "et all", in Slovak and Czech citations "a spol.".

Due to publishing of autodidactic tests it is necessary to add 4 questions to your article and 4 answers with marking of one correct answer, e.g.:

For primary dysmenorrhoea from laboratory results it is characteristic:
a. increase of lymphocytes in differential BP over 40 %
b. increase of C-reactive protein and FW in the blood
c. decrease of Hb level in the blood below 100 g/l
d. none of them are characteristic

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are double reviewed.

All published papers are paid.

Due to practical focus of the journal we would like to ask you to write the paper comprehensively, with emphasis on practical use of provided information in out-patient gynaecological practice.

Send contributions by e-mail to the address: paulenova@amedi.sk
Period 4x per year
1336-3425
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Gynecology for practice
Gynecology for practice
Reviewed, postgraduate scietific medical journal.
Period 4x per year