Ladislav Maršík, Andrea Ďurechová, Iveta Konýčková, Miroslav Borovský, Martin Petrenko, Viera Oroszová
The article gives an overview of opinions and information about native IVF cycles and IVF cycles with mild hormonal support on the basis of literature data and own experience. First child after extracorporeal fertilization was born in 1978, and was conceived in the native IVF cycle, too. The advantage of native IVF cycles versus IVF cycles after complete medication is the minimal burden for the patient, minimal risk of complications during oocyte collection, almost no risk of ovarian hyperstimulation syndrome, minimal risk of multi-foetal pregnancy, minimal or no cost to the cryopreservation of embryos and significantly lower total price of the cycle. The only disadvantage of native IVF cycles and IVF cycles with mild hormonal support is the lower success rate.