Slavomíra Kováčová
Multiple sclerosis is chronic autoimmune inflammatory and degenerative disorder of the central nervous system
with probably multifactorial etiology which mostly affect young people around age of 30. The most frequent form is relapse
remittent form which preferentially affects females with clinical onset often during child bearing years. So there
are many questions about disease impact on reproduction, gravidity and babies’ health as well. Fertility does not seem
to be impaired to a larger extent in women with multiple sclerosis. During pregnancy hormonal changes have beneficial
effect for disease activity suppression. Multiple sclerosis does not increase the risk of complication during gravidity
and there is also no negative effect on foetus and new-born provided there is an absence of other relevant problems.
The most risky period for reactivation of multiple sclerosis activity is during first 3 to 6 months after en_delivery. The strongest
predictor of postpartum relapses seems to be higher annual relapse rate prior to conception and during gravidity
as well as higher grade of disability in the beginning course of disease.