Zuzana Liptáková, Silvia Toporcerová, Peter Urdzík
Primary ovarian insufficiency is defined as the loss of the ovarian hormonal function in a woman before or at the age of
40. There are numerous markers of ovarian reserve, which are used to prognosticate the chances of pregnancy and success
with assisted reproductive techniques, namely, serum follicle-stimulating hormone, oestradiol, inhibin B, anti-
Mullerian hormone, ovarian volume and antral follicle count (AFC). The most accurate markers are AMH and AFC, but
we must also remember a female age when considering probability for getting pregnant. Increased infertility rates with
ageing are well documented despite good results of ovarian reserve tests. Proper population education should correct
reproductive behaviour and reduce the age of the firstborn and the percentage of women planning a pregnancy after
the age of 35.