Téma: Overview works

Peripheral nerves injury in the central nervous system degeneration: parkinsonism and related disorders and spinocerebellar ataxias

Zuzana Chovancová, Petr Kaňovský

Parkinsonian syndromes and spinocerebellar ataxia belong to a wider group family of neurodegenerative disorders. Their increasing incidence highlights the importance of correct diagnostics and therapy. In this context, conduction studies and needle electromyography can help in differential diagnosis. Neurophysiological examination may also provide information on the discussed contribution of peripheral neuropathy to etiology of gait disorder and falls, symptoms that are difficult to treat and significantly decrease the quality of life in Parkinsonian syndromes and spinocerebellar ataxias. Disadvantage of this method is lower specificity; therefore it is necessary to correlate the findings with the clinical neurological state.

Ročník 2008  Témy časopisu Neurology 1 / 2008

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doc. MUDr. Peter Špalek, PhD.
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Examples of citations:
1. Pitt B, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-717.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.

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Which of following factors is not related to rosacea?
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d. endothelial growth factor

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