Téma: Clinical pharmacology

Therapeutic use of transcranial doppler sonography in stroke patients – sono-thrombotripsy, sono-thrombolysis

David Školoudík, Michal Bar, Roman Herzig

Occlusion of intracranial or cervical artery is the most frequent cause of ischemic stroke. Recanalisation rate of the cerebral artery is one of the most important prognostic factors for independency of the patient after stroke. To speed up spontaneous recanalisation various pharmacological and mechanical methods have been used. One of them is monitoring of occluded artery by ultrasound – sono-trombolysis and sono-thrombotripse. The authors summarize their knowledge about the mechanism, safety and effectiveness of ultrasound monitoring with the use of diagnostic transcranial probes or non-diagnostic probes with loadbearing frequencies between 20 kHz and 2 MHz. Continual ultrasound monitoring of the occluded intracranial artery by diagnostic transcranial probe is a promising, safety and likely effective method that can lead to acceleration the recanalisation of the cerebral artery together with improving the neurological deficit.

Ročník 2008  Témy časopisu Neurology 3 / 2008

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