Ladislav Gurčík, Zuzana Gajdošová, Anna Tomášová, Peter Galik, Veronika Gašparíková, Anna Jarošová, Paulína Kubaľová, Slávka Lišková
The paper provides information about clinical symptoms, diagnostics and differential diagnostics of rare phenotypes of motoneuron disease – flail arm and flail leg syndrome. This syndrome is a variant of MND and differs from typical ALS in the initial symptoms, course and outcome of the disease. We present a case report of a patient with clinical and electrophysiological findings typical for the flail arm syndrome. Due to positivity for anti-ganglioside antibodies, we used intravenous administration of human immunoglobulin as a therapeutic test, however without desired result. The follow-ups showed that patient’s condition was deteriorating and the progress of the disease was inexorably proceeding.