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Časopis Neurology – Článok Painful sensomotoric polyneuropathy as a manifestation of epineural vessel vasculitis

Neurology

Reviewed, postgraduate scietific medical journal.
Period 3x per year
1336-8621
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
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Neurology
Neurology
Reviewed, postgraduate scietific medical journal.
Period 3x per year
Predplatné
Téma:  Case Studies

Painful sensomotoric polyneuropathy as a manifestation of epineural vessel vasculitis

Roman Sobota1, Berthold Kepplinger2

Vasculitides are the rare cause of polyneuropathy in which a definitive diagnosis is usually not possible only on the basis of clinical findings, but usually requires a biopsy of the damaged tissue. The case of a 58 year old patient with rapidly progressive polyneuropathy with the accentuation on the lower limbs has been reported. Clinically, the patient has been presented as a painful condition with significant plegia of peroneal muscle groups and mutually extinct tendo-periostal reflexes. The severe sensomotoric polyneuropathy with the accentuation on the lower limbs was found by electromyographic and electroneurographic examination. The only pathology found in the polyneuropathy screening was the positivity of p-ANCA (perinuclear antineutrophile cytoplasmic antibodies). The vasculitis of the mainly epineural larger caliber vessels was proved by the nerve and muscle biopsy and immunosuppressive therapy launched subsequently. In the treatment of pain, opioids and gabapentin have been deployed. Subjectively, the resolution of pain and after intensive rehabilitation the slight improvement of neurological deficiency occurred in patient. Despite the low incidence it is necessary in the framework of differential diagnosis of rapidly progressive polyneuropathy to think on the possibility of diagnosis of vasculitis.

polyneuropathy, vasculitis, nerve and muscle biopsy, immunosupressive treatment
Neurológia 2011; 6 (2): 86-89

Ročník 2011  Témy časopisu Neurology 2 / 2011

Overview works

Miroslav Brozman
Peter Špalek
Marián Kuchar
Ivan Gogolák
Pavel Šiarnik1, Lucia Krížová1, Branislav Kollár1, Marek Sýkora1,2, Peter Turčáni1

Case Studies

Roman Sobota1, Berthold Kepplinger2
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CHAIRMAN OF THE EDITORIAL BOARD
doc. MUDr. Miroslav Brozman, CSc.

MEMBERS OF THE EDITORIAL BOARD
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doc. MUDr. Eleonóra Klímová, CSc.
doc. MUDr. Pavol Kučera, PhD.
MUDr. Marian Kuchar, PhD.
doc. MUDr. Robert Mikulík,Ph.D., FESO
MUDr. Vladimír Nosáľ, PhD.
MUDr. Ľubica Procházková, CSc.
prof. MUDr. Bruno Rudinský, CSc.
doc. MUDr. Daniel Šaňák, Ph.D.
doc. MUDr. David Školoudík, Ph.D., FESO
prof. MUDr. Karel Šonka, DrSc.
doc. MUDr. Peter Špalek, PhD.
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2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
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Period 3x per year
1336-8621
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Neurology
Neurology
Reviewed, postgraduate scietific medical journal.
Period 3x per year
Predplatné