Darina Petrleničová, Ľubica Procházková
Multiple sclerosis (MS) is a chronical illness affecting mostly young people as they reach their most productive years. It is characterized by demyelinisation, axonal injury, inflammation and gliosis involving the brain, spinal cord and optic nerves. Resulting symptoms are both physical and psychological too, related to each other very closely. Cognitive and neurobehavioral problems associated with MS present serious psychosocial factor limiting the course of this disease. Almost 50 % of MS patients exprience depression and cognitive difficulties, as often as fatique and sleep disorders. Reports of schizophrenia and psychosis in MS were descibed. In our paper we present recent data about primary and secundary neuropsychiatric factors in MS.