Petr Kelbich1,2,6,9, Aleš Hejčl3,7,8,10, Jan Procházka4, Peter Čuchran5, Eva Hanuljaková2,9,12, Jitka Peruthová1,9,11, Martina Koudelková9
Inflammatory impairment of the central nervous system (CNS) usually projects to the composition of the cerebrospinal fluid (CSF). The goal of investigation of the CSF is to detect and specify the character of the inflammatory response, which significantly aids in the search for the cause of CNS impairment. First, the presence of immunocompetent cells, potential carriers of immune response in the CNS, should be determined. The next step should be to investigate a suitable functional parameter indicating the level of activation of these cells. For this purpose we derived the so called coefficient of energy balance (KEB) and have successfully used it for many years. The aim of our paper is to introduce this coefficient and demonstrate its significance in the diagnostics of inflammatory impairments of the CNS.