Martin Samohýl1, Ľubomír Lisý2, Jana Jurkovičová1
Multiple sclerosisis (SM) an autoimmune disease that affects the central nervous system (CNS) characterized by demyelination and axonal degeneration. The article highlights the impact of macro-and micronutrients in the treatment of multiple sclerosis. Particular attention is given to vitamin D. Proper nutrition in patients diagnosed with multiple sclerosis has the potential to improve the quality of life and to reduce the risk of chronic diseases. High serum levels of vitamin D are associated with the reduced risk of SM. Increased exposure of vitamin D may restore decreased activity of the target cell, due to the reduction of transcription, which may result in altered immunological profiles, or activities that contribute to the risk of multiple sclerosis. Multiple sclerosis is often associated with the vitamin B12 deficiency, which can be detected at any stage of clinical progression of SM.