František Jurčaga, Martin Mistrík, Daša Marecová, Zuzana Hudecová
Sclerosis multiplex (SM) is a chronic inflammatory autoimmune and neurodegenerative disease of heterogeneous
aetiopathogenesis with manifestations of white and grey mass impairment of a focal as well as diffuse character,
which without treatment causes significant disability in the majority of patients. It manifests as a disease of thousand
faces and determination of final diagnosis might be problematic in an atypical course. Hairy cell leukaemia
(HCL) is rarely occurring leukaemia, which ranks among non-Hodgkin lymphomas with low malignity. The coincidence
of both diseases is extremely rare and just several cases were described in the literature. It is interesting is
that in this case 2-deoxyadenosine (Cladribine) is used therapeutically, which is the medication of choice in HCL
treatment and its effectiveness is also proved in the SM treatm ent.