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Časopis Neurology – Článok Magnetic resonance and its importance in the diagnosis of sclerosis multiplex (SM)

Neurology

Reviewed, postgraduate scietific medical journal.
Period 3x per year
1336-8621
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Neurology
Neurology
Reviewed, postgraduate scietific medical journal.
Period 3x per year
Predplatné
Téma: Overview works

Magnetic resonance and its importance in the diagnosis of sclerosis multiplex (SM)

Marek Tarčák, Veronika Vajdová

Sclerosis multiplex (SM) is a disease of the central nervous system (CNS) characterized with the inflammation, demyelination and neurodegeneration and it is very often a non-traumatic cause of neurological disability in young people(1). Episodes of focal infiltration of nervous issues with lymphocytes with subsequent destruction of myelin and axons are typical(2). The disease presents in each patient individually and while one group of patients reaches through their life a low score of disability (expressed with Kurtze scale of disability, Expand Disability Status Score - EDSS), others suffering from aggressive SM form reach a high EDSS in a relatively short time. In the pathogenesis of the disease many mechanisms are applied, which do not cause just local damage of the tissue but also lead to an important reduction of the parenchyma in the brain and spinal cord and finally to a permanent disability of a patient.
At present, brain and spinal cord imaging with magnetic resonance (MRI) has a significant role in the differential SM diagnosis, in monitoring of the activities of the disease itself, in the choice of a suitable therapy for a patient and evaluation of its effectiveness, in early detection of adverse effects of the treatment and in determination of the diagnosis. MRI examination is characterized by high sensitivity for early detection of the disease. However, the specificity of the examination is low. In patients with Clinically Isolated Syndromes (CIS) as optic neuritis, the syndrome of the brain stem or syndrome of the spinal cord, MRI might support or replace clinical manifestations based on the evaluation of the presence of demyelination lesions in the development of the disease. Not each CIS progresses to SM; however, the presence of T2 hyper intensive lesions on the MRI examination is related to the higher risk of SM origination and gradual disability. The MRI examination is also a key one in the exclusion of other diseases, which might simulate SM in the clinical picture(3,4).

sclerosis multiplex, magnetic resonance, McDonald’s criteria, liquor examination
Neurológia 2019; 14 (2): 79-81

Ročník 2019  Témy časopisu Neurology 2 / 2019

Original works

Ivan Martinka, Peter Špalek, Lenka Fajkusová
Terézia Mazúrová, Ema Kantorová, Egon Kurča, Štefan Sivák

Overview works

Jan Krejsek
Marek Tarčák, Veronika Vajdová
Slavomíra Kováčová
René Opšenák, Pavol Snopko, Martin Hanko, Kristián Varga, Tomáš Fejerčák, Radoslav Hanzel, Mária Masaryková, Branislav Kolarovszki
David Černík, Filip Cihlář, Daniel Šaňák
Daniela Botiková, Stanislav Voháňka

Case studies

Ladislav Gurčík, Peter Špalek, František Cibulčík
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CHAIRMAN OF THE EDITORIAL BOARD
doc. MUDr. Miroslav Brozman, CSc.

MEMBERS OF THE EDITORIAL BOARD
MUDr. František Cibulčík, CSc.
doc. MUDr. Eleonóra Klímová, CSc.
doc. MUDr. Pavol Kučera, PhD.
MUDr. Marian Kuchar, PhD.
doc. MUDr. Robert Mikulík,Ph.D., FESO
MUDr. Vladimír Nosáľ, PhD.
MUDr. Ľubica Procházková, CSc.
prof. MUDr. Bruno Rudinský, CSc.
doc. MUDr. Daniel Šaňák, Ph.D.
doc. MUDr. David Školoudík, Ph.D., FESO
prof. MUDr. Karel Šonka, DrSc.
doc. MUDr. Peter Špalek, PhD.
Dr. Milan R. Voško, PhD.

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Eva Stachová
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SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum size is 7 pages (font size 12, line spacing 1.5) with maximum 6 pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with emphasis on its practical usage for neurologists.

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MANUSCRIPT ELABORATION

Write the paper on computer in any common text editor.
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- distinguish precisely numbers 1, 0 and letters l, O
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MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - concise content summary in the extent maximum 10 lines (only at overview papers, case studies and Appendices - General Medicine). Write in 1st or 3rd person singular or plural (unify according the type of an article).
3. Key words - in the extent of 3-6 (only for overview papers and Appendices - General Medicine).
4. English translation: paper title, summary, key words (only at overview papers, and Appendices - General Medicine)
5. Text
If you insert pictures into a document, send also their original files in "jpg" format, create graphs in Excel and send also their original files. If you send photo documentation via post office, please, send just high-class originals. Mark each original by a number, under which it is mentioned in the text. Write in 1st or 3rd person singular or plural (unify according the type of an article).
6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses. Use maximum 20 citations.

Examples of citations:
1. Pitt B, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-717.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages. If an author is one, two or three - it is necessary to state all. If there are more than three authors it is necessary to write first three and "et all".

Due to publishing of autodidactic tests it is necessary to add 4 questions to your article and 4 answers with marking of one correct answer, e.g.:

Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

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Due to practical focus of the journal we would like to ask you to write the paper comprehensively, with emphasis on practical use of provided information in out-patient neurological practice.

Send contributions in the e-mail to the address: stachova@amedi.sk
Period 3x per year
1336-8621
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Neurology
Neurology
Reviewed, postgraduate scietific medical journal.
Period 3x per year
Predplatné