Ján Grossmann, Ema Kantorová, Štefan Sivák, Slavomíra Kováčová, Egon Kurča
Multiple Sclerosis (SM) is a chronic and progressive demyelinating inflammatory disease of the central nervous system (CNS). Cognitive disorders in multiple sclerosis are among the core features of MS. They occur already in the early stages of the disease and it is not yet clear which neuropathological processes affect them. Neuropsychological examination can be used to assess disease progression without radiological findings and visible neurological symptoms. The process of neuropsychological examination is quite demanding and requires good cooperation between the patient and the neuropsychologist. A decrease in cognitive functions, as measured in some measures during multiple examinations, has been shown to mean suboptimal effectiveness of DMD treatment and suggests a change in DMD treatment.