Téma: 

Histopathological characteristics of bladder tumours: analysis of own material according to who classification 2004

Michal Horňák, Štefan Galbavý, Augustín Bárdoš

Objective: In order to achieve an objective prediction of biologic behaviour of bladder tumours, in 2004 WHO published new histopathological classification. This paper describes the incidence of tumours in their morphological groups according to WHO classification 2004 and compares it with incidence of tumours classified according to WHO classification 1973. Material and methods: In 2004 and 2005 there were 105 patients diagnosed with bladder tumours, the mean age of patients was 68.6 ± 10.6 years (range 29 - 90). The histopathological characteristics of bladder tumours were assessed by using WHO classification 2004. Results: Type of tumours – papiloma 1 (1.0 %); Ta stage 58 (55.2 %); T1 stage 12 (11.4 %); T2-4 stages 34 (32.4 %). 56.2 % of these tumours were non-invasive and 43.8 % were invasive. In 58 patients in stage Ta none of the patients had papillary urothelial neoplasia of low malignant potential (PUNLMP), low-grade urothelial carcinoma was diagnosed in 44 (41.9 %) and high- grade urothelial carcinoma in 14 patients (13.3 %). All patients in T1 stage had a high-grade urothelial carcinoma. Second repeated transurethral resection of bladder tumours was performed in 23 of 26 patients (Ta and T1 stage) and in 15 cases (65.2 %) it was positive. Conclusions: Correlation of histopathological characteristics of bladder tumours evaluated by WHO classification 1973 and WHO classification 2004 has shown progression towards high-grade urothelial carcinoma in patients assessed by the new classification.

Ročník 2006  Témy časopisu Clinical urology 2 / 2006

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