1Martin Romančík, 1Peter Weibl, 2Viera Labudová, 1Ivan Lutter, 1Milan Obšitník, 3Frederico Goncalves
Objective: To compare early results of transobturator tape (TOT) implantation in women with stress urinary incontinence (SUI) stratified by Valsalva leak point pressure (VLPP) value, to find out significant and independent significant prognostic factors of TOT implantation. Material and Methods: 97 female patients (pts) underwent TOT implantation between March 2004 and September 2007. Their inclusion criteria were urodynamic SUI, the exclusion criteria were detrusor overactivity or underactivity, neurogenic voiding dysfunction, pelvic organ prolapse and post-void residuum higher than 40 ml. Following preoperative parameters were observed in all patients: VLPP, urine leakage (PWT1), quality of life (IQOL1), age, BMI, parity, previous anti-incontinence surgery, hysterectomy status (HYE) and symptoms of overactive bladder. Pts were introduced into two groups according to their VLPP value: pts with lower VLPP values (≤ 60 cm H2O) and pts with higher VLPP values (> 60 cm H2O). Two different tapes were used for TOT implantation (resorbable and nonresorbable). Six months after surgery urine leakage (PWT2), quality of life (IQOL2) and complications of surgery were established. Pts were classified into two main categories: cured (PWT2 ≤ 2 g) and not cured (PWT2 > 2 g). Results: Pts with lower VLPP values had significantly lower cure rate than those with higher VLPP values (43.8 % versus 81.5 %, p < 0.001, respectively). Pts with lower VLPP values had 5-fold greater risk for not being cured than those with higher VLPP values. Univariate logistic regression analysis identified PWT1, age, VLPP, IQOL1, TOT type and HYE as significant prognostic factors for cure. Multivariate logistic regression analysis identified from these significant prognostic factors only PWT1 and TOT type as independent ones. The area under the ROC curve of multivariate model PWT1 + TOT type and model VLPP + TOT type are comparable (0.89627 a 0.84129, respectively). Conclusions: Lower VLPP value represents a significant prognostic factor for not being cured after TOT implantation. The use of resorbable TOT significantly increases the risk for not being cured.