Téma: Overview works

The neoadjuvant treatment and adjuvant chemotherapy of muscle invasive bladder cancer in the context of interdisciplinary collaboration

Patrik Palacka, Jana Obertová

Bladder cancer is the most frequent malignant disease of urinary system with slowly increasing incidence. Neoadjuvant and/ or adjuvant chemotherapy in patients with muscle invasive bladder cancer is still discussed. The objective of the review is to analyse published clinical trials and formulate recommendations for clinical practitioners. On the basis of available data, neoadjuvant treatment with cisplatin is currently recommended in every patient with muscle invasive bladder cancer with planned cystectomy due to improved overall survival. Adjuvant chemotherapy is recommended to every patient after cystectomy for T3-T4 bladder cancer and/or positive lymphatic nodes. Another clinical trials should answer the question of optimal sequence neoadjuvant/adjuvant chemotherapy and surgical approach.

Ročník 2010  Témy časopisu Clinical urology 3 / 2010

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prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
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prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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prof. MUDr. Ján Švihra, PhD.

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Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981:15-27.

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Which of following factors is not related to rosacea?
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b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

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