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Časopis Clinical urology – Článok Systemic treatment of muscle-infiltrating urothelial carcinoma of the bladder

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: 

Systemic treatment of muscle-infiltrating urothelial carcinoma of the bladder

Jana Obertová

Bladder cancer is the most common malignancy involving the urinary system. Urothelial (transitional cell) carcinoma is a predominant histologic type in Europe, where it accounts for 90 % of all bladder cancers. Much less commonly, urothelial cancers can arise in the renal pelvis, ureter, or urethra. Approximately 25 % of patients have muscle-invasive disease and at the time of diagnostics they have either present or later developed metastases. Systemic chemotherapy is a standard approach for patients with inoperable locally advanced or metastatic urothelial malignancies. Although initial response rates are high (about 50 %), the median survival with multiagent chemotherapy is about 15 months. While this is superior to the estimated six-month survival with metastatic disease prior to the development of modern chemotherapy regimens, the five-year survival rate is about 15 % with contemporary regimens. The approach to systemic treatment for metastatic disease of urothelial cancer of the renal pelvis or ureter is based upon results from trials composed primarily of patients with urothelial carcinoma of the bladder. Systemic chemotherapy for metastatic urothelial cancer and the use of chemotherapy as a neoadjuvant or adjuvant combined with cystectomy is reviewed here.

urinary bladder, urothelial cancer, systemic therapy, chemotherapy
Klin. urol. 2013; 9 (2-3): 82-89

Ročník 2013  Témy časopisu Clinical urology 2 / 2013

Martina Ondrušová1,2,3, Veronika Šťastná4, Dalibor Ondruš5
Štefan Galbavý
Juraj Fillo
Jana Obertová
Ján Ľupták, Ján Švihra, Boris Eliáš
Vladimír Bartoš1, Juraj Mikuláš2, Roman Mráz2
Peter Čech1, Ján Ľupták2, Peter Slezák3

Case Studies

Peter Čech, Romana Hubináková, Jana Mrážiková

M. E. Lipkin a G. M. Preminger

Overview works

Milan Šobek
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3 1
3 1
3 1
3 2 1
3 1
3 1
2 1
2 1
3 2 1
3 2 1
2 1
3 2 1
3 2 1
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Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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prof. MUDr. Ján Švihra, PhD.

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The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum extent is 7 pages of text (font ARIAL or TIMES, font size 12, line spacing 1.5). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office.

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Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses.
Citation means in general: the surname of the author (authors), title of the work, year of issuing, volume, pages.
Do not use "ét al.", but state all authors.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

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Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné