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Časopis Clinical urology – Článok Is there an equivalent of polycystic ovary syndrome in men? preliminary results of a pilot

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: 

Is there an equivalent of polycystic ovary syndrome in men? preliminary results of a pilot

Vincent Nagy1, Ivica Lazúrová2, Ingrid Dravecká2, Jagienka Jautová3, Janette Baloghová3, Ladislav Valanský1, Ľubomír Lachváč1

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women in reproductive age. Given the complexity of related symptoms of women with PCOS and signs of autosomal inheritance it is presumed to have been the male equivalent of PCOS. Objective of the study: The aim was to determine the existence of a male equivalent of polycystic ovary syndrome (PCOS) in younger men with hormonal imbalance and androgenic alopecia. Clinical material and methods: In 2010-2011 there 22 patients with a mean age of 31.7 ± 7.9 years were examined. Dermatological examination to exclude other causes of alopecia (16/22 in the skin biopsy), urological (sexological) and internal examination were provided. There were examined plasma glucose and insulin levels, with the calculation of insulin resistance index HOMA (Homeostasis Model Assessment: glucose x insulin /22.5), lipids: total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides. In all patients basic hormonal spectrum and anthropometric parameters were examined: total and free testosterone, free androgen index (FAI), sexual hormone binding globulin (SHBG), follicle stimulating hormone (FSH), luteinizing hormone (LH) and anthropometric parameters: weight, height, waist circumference and body mass index (BMI: weight/height2). Results: New onset type 2 diabetes was confirmed in one patient (4.5 %) and insulin resistance was confirmed in three patients (13.6 %). Metabolic dyslipidaemia (hypertriglyceridemia, low HDL cholesterol or elevated LDL cholesterol) occurred in 8 patients (36 %). Increased levels of testosterone were found in only one patient (4.5 %), increased FAI in four patients (18.18 %), and decreased SHBG in two subjects (9 %). Overweight and obesity have been confirmed in 40 % (9 patients). Conclusion: The existence of male equivalent of PCOS has not yet been proven, but there were confirmed features of the metabolic syndrome, marginally higher fasting blood glucose, elevated LDL cholesterol and overweight. There were found significant changes in hormonal parameters.

androgens, alopecia, PCOS, male equivalent, diabetes mellitus
Klin. urol. 2014; 10 (1): 32-35

Ročník 2014  Témy časopisu Clinical urology 1 / 2014

Vladimír Bartoš1, Juraj Mikuláš2, Roman Mráz2
Jozef Marenčák, Rudolf Moro, Eduard Králik, Patrícia Rusková

Jozef Marenčák, Rudolf Moro, Eduard Králik, Dymitry Lapatko
Michal Peteja, Ivan Viľcha, Ivan Minčík, Richard Ľuník

Vincent Nagy1, Ivica Lazúrová2, Ingrid Dravecká2, Jagienka Jautová3, Janette Baloghová3, Ladislav Valanský1, Ľubomír Lachváč1
Monika Kmeťová-Sivoňová1, Marta Vilčková1, Svetlana Grobarčíková2, Jana Jurečeková1, Dušan Dobrota1, Ján Kliment2

Jaroslav Beck1, Tatiana Baltesová2, Ľuboš Tešľa1, Štefan Hulík3, Erik Tóth3, Vincent Nagy1, Ladislav Valanský1, Ľuboslav Beňa2, Peter Závacký3

Ľuboš Tešľa, Vincent Nagy
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The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné