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Časopis Clinical urology – Článok Conservative (non-surgical) treatment of induratio penis plastica

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: 

Conservative (non-surgical) treatment of induratio penis plastica

Jozef Marenčák

Induratio penis plastica (IPP, Peyronie´s disease) is a connective tissue disorder, characterised by the formation of a fibrotic
lesion or plaque in the tunica albuginea, which leads to penile deformity. Prevalence rates of 0.4 – 9 % have been
published. The aetiology of IPP is unknown. The contribution of associated comorbidities or risk factors (e. g. diabetes
mellitus, hypertension, lipid abnormalities and Dupuytren´s contracture) to the pathophysiology of Peyronie´s disease
is still unclear. Two phases of the disease can be distinguished. The first phase is the acute inflammatory phase (painful
erections, „soft“ nodule/ plaque), and the second phase is the fibrotic/calcifying phase with formation of hard palpable
plaques (disease stabilisation). Spontaneous resolution is uncommon (3 – 13 %) and most patients experience disease
progression (30 – 50 %) or stabilisation (47 – 67 %). Pain is usually present during the early stages of the disease but
tends to resolve with time in 90 % of men. Conservative treatment for Peyronie´s disease is primarily aimed at treating
patients in the early stage of the disease. It is an option in patients not fit for surgery or when surgery is not acceptable
to the patient. In this context, several options have been suggested, including oral pharmacotherapy, intralesional injection
therapy and other topical treatments, which will be discussed in detail in this review en_article. The role of conservative
treatment in men with stable/chronic disease has not been adequately defined yet. No a single drug has been approved
(grade A recommendation) by the European Medical Association for the therapy of this relatively rare disease.

induratio penis plastica, conservative treatment
Klin. urol. 2015; 11 (1): 41-46

Ročník 2015  Témy časopisu Clinical urology 1 / 2015

Jana Katolická
Terézia Jankovichová, Martin Jankovich

Jaroslav Ženíšek
Ján Švihra, Martin Benčo, Róbert Dušenka, Ján Ľupták, Ján Kliment
Martin Jankovich, Terézia Jankovichová

Jozef Marenčák, Rudolf Moro, Dymitry Lapatko, Michaela Trabalíková

Juraj Fillo, Michaela Levčíková, Ján Luha, Ján Breza, Anna Vachulová, Štefan Durdík, Peter Labaš, Martina Ondrušová
Jozef Marenčák
Silvester Galo, Pavol Žúbor, Soňa Kulichová, Dana Rybárová
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Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

PROFESSIONAL EDITOR
prof. MUDr. Ján Švihra, PhD.

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Ing. Danica Paulenová
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1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - structured abstract: goal of work, material and methods (do not state the name of the workplace), results, conclusion
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Write in 1st or 3rd person singular or plural (unify according the type of an article).
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6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses.
Citation means in general: the surname of the author (authors), title of the work, year of issuing, volume, pages.
Do not use "ét al.", but state all authors.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981:15-27.

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages.

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

All published papers are paid.

Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné