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Časopis Clinical urology – Článok The testosterone deficiency syndrome in aging males

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: OVERVIEW WORKS

The testosterone deficiency syndrome in aging males

Jozef Marenčák

The elderly population is the fastest growing age group and needs a considerable attention. Androgen decline represents
one of the most important medical aspect of elderly. Testosterone Deficiency Syndrome (TDS) is a clinical and biochemical
syndrome which results in significant detriment in the quality of life and adversely affects the function of multiple
organ systems. The pathophysiology of testosterone (T) decline in elderly is not yet completely defined. Potential
mechanisms include reduced hypothalamic GnRH outflow, impaired testicular steroidogenesis and altered sex – steroid
negative feedback. Androgen pharmaceutical worldwide marketplace has largely changed during last years by introduction
of new oral, parenteral and transdermal preparations. T supplementation is safe and efficacious in improving
symptoms associated with androgen deficiency. Risks of androgen replacement therapy (ART) are mild and contraindications
for T treatment well defined. A close monitoring during T administration is needed and timing and modalities
are very well indicated. One of the most controversial aspects of the ART remains the effect of T on prostate functioning.
To date, prospective studies have demonstrated a low frequency of prostate cancer in association with T replacement
therapy (TRP). Current standard of practice established categorically that the administration of androgen is absolutely
contraindicated in men suspected of or harbouring prostate and breast cancer. This includes those with an abnormal
digital rectal examination (DRE) and/ or abnormal prostate specific antigen (PSA), in whom the diagnosis of carcinoma
has not been excluded beyond doubt. There is not now – nor has there ever been – a scientific proof for the belief that
T causes prostate cancer to grow. Larger – scale and longer – term data are needed on the effects of T treatment in the
older population to confirm safety on specific risk data on the prostate and cardiovascular systems.

TDS, diagnosis, treatment, efficiency, safety
Klin. urol. 2015; 11 (3): 61-66

Ročník 2015  Témy časopisu Clinical urology 3 / 2015

OVERVIEW WORKS

Jozef Marenčák
Peter Gavorník, Ján Breza ml., Andrej Dukát, Ľudovít Gašpar, Eva Cikatricisová, Xénia Faktorová, Iveta Gašparová, Ján Breza st.

Katarína Rejleková
Soňa Balogová, Lucia Noskovičová, Marika Vereb, Lucia Kaliská
Branislav Obšitník, Pavol Lukačko, Alžbeta Molnárová, Jozef Greždo, Kristína Poláková
Ivan Perečinský, Ivan Minčík

CASE STUDIES

Gabriel Bognár, Katarína Macháleková, Csaba Biró, Štefan Galbavý, Karol Kajo

VARIOUS

Petra Skalová, Martin Vojtko, Denisa Osinová, Slavomíra Lauková
Ivan Minčík, Ivan Perečinský
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Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

PROFESSIONAL EDITOR
prof. MUDr. Ján Švihra, PhD.

EDITOR-IN-CHIEF
Ing. Danica Paulenová
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SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum extent is 7 pages of text (font ARIAL or TIMES, font size 12, line spacing 1.5). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office.

ORIGINAL PAPERS
Structuring: introduction, clinical group and methods, results, discussion, conclusion, bibliography

DIAGNOSTIC AND THERAPEUTICAL ALGORITHMS
Diagnosis and therapy processed into tables and schemes, with minimum text, with emphasis on conciseness and clarity.

CASE STUDY
Maximum extent is 3 pages. Structuring: summary, case study, conclusion, bibliography.

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MANUSCRIPT ELABORATION

Write the paper on computer in any common text editor.
write full length of lines (do not use ENTER at the end of a line)
- do not arrange text into columns
- do not do page make-up, put tables at the end of the paper
- distinguish precisely numbers 1, 0 and letters l, O
- use always parentheses ( )
- explain abbreviations always when first used


MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - structured abstract: goal of work, material and methods (do not state the name of the workplace), results, conclusion
3. Key words - in the extent of 3-6.
Write in 1st or 3rd person singular or plural (unify according the type of an article).
4. English translation: the title of the paper, summary, key words 5. Text
If you insert pictures into a document, send also their original files in "jpg" format, create graphs in Excel and send also their original files. If you send photo documentation via post office, please, send just high-class originals. Mark each original by a number, under which it is mentioned in the text. Write in 1st or 3rd person singular or plural (unify according the type of an article). In the text do not use highlighting of the text as e.g. underlined text, bold, with exception of titles, references to pictures, tables, graphs.

6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses.
Citation means in general: the surname of the author (authors), title of the work, year of issuing, volume, pages.
Do not use "ét al.", but state all authors.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981:15-27.

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages.

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

All published papers are paid.

Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné