Amedi.sk
Dovoľujeme si Vás upozorniť, že naša web stránka
je určená iba pre odbornú lekársku verejnosť.
Časopis Clinical urology – Článok Overall survival of patients with sarcomatoid dedifferentiation of kidney cancer

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: 

Overall survival of patients with sarcomatoid dedifferentiation of kidney cancer

Ján Šulgan, Martin Jonáš, Roman Tomaškin, Ján Švihra, Eliáš Boris, Pavol Slávik, Ján Ľupták

Objectives: The aim of the study is a retrospective evaluation of patients with sarcomatoid variant of kidney cancer that
underwent the surgery at our institution. We focused on the disease stage at the time of diagnosis and overall survival
after surgery.
Methods: Seventy two patients were treated at our institution between 2004 and 2014. Patients underwent radical nephrectomy
(open or laparoscopic), lymphadenectomy in case of clinically positive lymphatic nodes, metastasectomy for
solitary resectable metastasis and cytoreductive nephrectomy in a small group of patients. The data for analysis were
gathered from medical records at our department. We used standard descriptive and analytical statistical methods, including
Kaplan-Meier survival analysis.
Results: In all, 72 patients with median of age 62.7 years (range 40 – 84 years) were included in the study with identical
number of men and women, i.e. 36 (50%). Average longest diameter of tumour was 9.1 cm (SD ± 3.6 cm). Fuhrman nuclear
grading was G4 in all cases (by definition?). The T stage was the following: T1 10 (13.9%), T2 2 (2.8%), T3a 28 (38.8%),
T3b 24 (33.3%) and T4 8 (11.1%). Metastatic lymph nodes were found in 14 (19.4%). Distant metastases were observed/
diagnosed in 25 (34.7%) patients. The dominating surgical technique was transperitoneal approach in 67 (93.1%) cases.
Overall survival was 76.3% in first years of follow-up, but in the second year it declined to 47.2%. Overall survival was
36.1% after 3 years and 26% after 4 years of follow-up. At the end of 5 year period only 20% of patients survived.
Conclusion: Dedifferentiated sarcomatoid cancer is biologically and clinically the most aggressive type of kidney cancer.
Currently, we do not have multicentric randomized trials dealing with its early diagnosis and treatment. Consistent
understanding of its biological behaviour, intensified monitoring of post-operative follow-up, aggressive surgical
and medical therapy are important factors contributing to improvement of the prognosis of patients with this histological
type of the tumour.

sarcomatoid renal cell carcinoma, overall survival
Klin. urol. 2016; 12 (1): 18-21

Ročník 2016  Témy časopisu Clinical urology 1 / 2016

Vladimír Baláž, Jozef Babeľa, Pavel Bican, Terézia Stančoková
Ján Kliment st., Hubert Poláček, Ivan Režňák
Ján Šulgan, Martin Jonáš, Roman Tomaškin, Ján Švihra, Eliáš Boris, Pavol Slávik, Ján Ľupták
Jozef Marenčák

Zuzana Nosáľová, Vincent Nagy, Miroslav Iláš , Ľubomír Lachváč
Jozef Marenčák, Eduard Králik, Patrícia Rusková, Lenka Kotorová, Michaela Trabalíková

Ján Breza ml., Zuzana Žilinská, Martin Chrastina, Miroslava Sersenová, Branislav Trebatický,Peter Bujdák, Ján Breza st.

CASE STUDIES

Marek Gojdič, Ján Breza, ml., Katarína Macháleková, Štefan Galbavý, Ján Breza, st.
1
3 1
3 1
3 1
3 1
3 1
2 1
2 1
2 1
3 2 1
3 2 1
2 1
3 2 1
3 2 1
1
Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

PROFESSIONAL EDITOR
prof. MUDr. Ján Švihra, PhD.

EDITOR-IN-CHIEF
Ing. Danica Paulenová
e-mail: paulenova@amedi.sk

GRAPHIC LAYOUT AND TYPESETTING
Lucia Vecseiová
e-mail: dtp@amedi.sk

MARKETING MANAGER
Ing. Dana Chodasová
mobil: 0903 224 625
e-mail: marketing@amedi.sk

ECONOMY AND SUBSCRIPTIONS
Ing. Mária Štecková
telefón: 02/55 64 72 48
mobil: 0911 117 949
e-mail: ekonom@amedi.sk

LANGUAGE PROOFREADING
Mgr. Eva Doktorová

PROOFREADING OF ENGLISH TEXTS
Mgr. Jana Bábelová
SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum extent is 7 pages of text (font ARIAL or TIMES, font size 12, line spacing 1.5). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office.

ORIGINAL PAPERS
Structuring: introduction, clinical group and methods, results, discussion, conclusion, bibliography

DIAGNOSTIC AND THERAPEUTICAL ALGORITHMS
Diagnosis and therapy processed into tables and schemes, with minimum text, with emphasis on conciseness and clarity.

CASE STUDY
Maximum extent is 3 pages. Structuring: summary, case study, conclusion, bibliography.

MISCELLANEOUS
Reaction to overview articles, news in the field of diagnostics, therapy, trial results (maximum 3 pages), reports from professional events, abstracts from scientific work published abroad, not older than 1 year. Maximum extend is 1 page. Title of the paper in Slovak/Czech, authors, workplace, then title of the paper in English with full citation.


MANUSCRIPT ELABORATION

Write the paper on computer in any common text editor.
write full length of lines (do not use ENTER at the end of a line)
- do not arrange text into columns
- do not do page make-up, put tables at the end of the paper
- distinguish precisely numbers 1, 0 and letters l, O
- use always parentheses ( )
- explain abbreviations always when first used


MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - structured abstract: goal of work, material and methods (do not state the name of the workplace), results, conclusion
3. Key words - in the extent of 3-6.
Write in 1st or 3rd person singular or plural (unify according the type of an article).
4. English translation: the title of the paper, summary, key words 5. Text
If you insert pictures into a document, send also their original files in "jpg" format, create graphs in Excel and send also their original files. If you send photo documentation via post office, please, send just high-class originals. Mark each original by a number, under which it is mentioned in the text. Write in 1st or 3rd person singular or plural (unify according the type of an article). In the text do not use highlighting of the text as e.g. underlined text, bold, with exception of titles, references to pictures, tables, graphs.

6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses.
Citation means in general: the surname of the author (authors), title of the work, year of issuing, volume, pages.
Do not use "ét al.", but state all authors.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981:15-27.

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages.

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

All published papers are paid.

Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné