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Časopis Clinical urology – Článok Testosterone and its role in prediction of pathological condition after radical prostatectomy in prostate cancer patients

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: 

Testosterone and its role in prediction of pathological condition after radical prostatectomy in prostate cancer patients

Henrieta Drobková, Jana Jurečeková, Marián Grendár, Ján Kliment Jr., Erika Halašová, Ján Kliment

Objective: The objective of the study was to assess the association between the level of total serum testosterone in prostate
cancer patients before radical prostatectomy and pathological Gleason score and pathological stage.
Material and Methods: We measured preoperative levels of total circulating testosterone by the chemiluminescence
method in peripheral blood samples in 201 Slovak prostate cancer patients. In all patients, their age was listed, and we
also assessed other preoperative and postoperative (pathological Gleason score and pathological stage) data/prognostic
factors by multiple types of examinations. We used multinomial logistic regression to evaluate the potential use of
total testosterone as a possible predictor of the pathological Gleason score and pathological stage.
Results: We have found a highly significant association between age and total preoperative testosterone (p-value = 0)
in men with prostate cancer. The results also pointed to the fact that total serum testosterone (as a single predictor, or
in combination with other preoperative prognostic factors – PSA in peripheral blood, clinical stage and biopsy Gleason
score) is not a statistically significant predictor of the pathological Gleason score and pathological stage.
Conclusion: Despite the fact that testosterone plays a crucial role in carcinogenesis of the prostate, total serum testosterone
was not a statistically significant predictor of pathological Gleason score and pathological stage in the population
of Slovak men.

prostate cancer, total serum testosterone, pathological Gleason score, pathological stage, age
Klin urol 2017; 13 (1): 21 – 25

Ročník 2017  Témy časopisu Clinical urology 1 / 2017

Martina Ondrušová, Dalibor Ondruš
Peter Ščešňák, Ivan Minčík
Jana Katolická
Henrieta Drobková, Jana Jurečeková, Marián Grendár, Ján Kliment Jr., Erika Halašová, Ján Kliment
Róbert Dušenka, Svetlana Dušenková, Boris Eliáš, Pavol Slávik, Ján Švihra st., Ján Ľupták, Ján Kliment st.
Ladislav Macko, Ján Kliment
Ján Švihra, Róbert Dušenka, Ján Ľupták, Igor Sopilko, Viera Švihrová
Michal Pokusa, Alžbeta Trančíková, Ján Švihra, Marián Kollárik, Róbert Dušenka, Ján Ľupták, Miloš Tatár
Viktor Kováčik, Peter Bujdák, Vladimír Baláž
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CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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prof. MUDr. Ján Švihra, PhD.

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2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Which of following factors is not related to rosacea?
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c. propionibacterium acnes
d. endothelial growth factor

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Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné