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Časopis Clinical urology – Článok Current view of penile cancer

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: Urological oncology

Current view of penile cancer

Jozef Marenčák

The incidence of penile cancer (PeC) in Europe lies in the range of 0.9 to 2.1 cases per 100 000 persons per year. Carcinogenesis is associated with human papilloma virus (HPV) infection and with chronic inflammation. 95 % of cases of PeC are accounted for squamous cell carcinoma (SCC), whose numerous subtypes have different clinical courses. Chronic preputial inflammation due to phimosis or lichen sclerosus is often associated with PeC. Circumcision lowers the risk of penile cancer (hazard ratio: 0.33). Maximally organ – preserving surgery with safety margins of no more than a few millimeters is the current therapeutic standard, because a local recurrence, if it arises, can still be treated locally with curative intent. Local radiotherapy (RT) can be performed in early stages. Lymphogenic metastasis must be treated with radical lymphadenectomy (LAD) and adjuvant chemotherapy (CHT). Patients with clinically unremarkable inguinal lymph nodes (LNs), nonetheless, need invasive lymph node staging because of the high rate of lymphogenic micrometastasis. PeC is curable in all early stages with the appropriate treatment, but its prognosis depends crucially on the proper management of the regional (especially inguinal) LNs. In many countries, the treatment of this rare disease entity has already been centralized. This article summarizes the current knowledge of the disease and the management strategies for penile cancer. The aim of this paper is to highlight the complexity of this cancer and to show that delayed or incorrect treatment can be life – threatening.

penile cancer, etiopathogenesis, diagnosis, therapy
Klin urol 2019; 15 (1): 12 – 18

Ročník 2019  Témy časopisu Clinical urology 1 / 2019

Urological oncology

Pavol Dubinský
Jozef Marenčák
Vincent Nagy, Miroslav Iláš, Ladislav Valanský, Ľubomír Lachváč, Jaroslav Beck, Vladimíra Sobolová, Patrícia Horváthová, Lucia Kišáková
Magdaléna Božiková, Vladimír Baláž

Funkcional urology

Alena Buková, Magdaléna Hagovská, Ján Švihra, Agata Hrobacz, Dana Dračková
Ľubomír Lachváč
Vincent Nagy
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CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
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prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Which of following factors is not related to rosacea?
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b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

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Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné