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Časopis Clinical urology – Článok Novel non-invasive molecular and fluorescent methods in the detection of bladder tumours

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: Urological oncology

Novel non-invasive molecular and fluorescent methods in the detection of bladder tumours

Vladimíra Sobolová, Vincent Nagy

The article offers information about new approaches in the diagnosis and monitoring of bladder cancer by molecular and fluorescence analysis methods. Listed methods are used for detection of micro RNA, hypoxia-induced factor and fluorescence urine examination. MicroRNA (miRNA) is a single stranded small non-coding RNA consisting of 19-25 nucleotides in length. Its role is to participate in the regulation of gene expression, where it plays the role of the silencer. Expression of regulation is based on base pairing with a gene for transcription of a target protein that results in a decrease in regulation or repression of the target gene. Hypoxia-induced factor 1 (HIF-1) is a transcription factor sensitive to the oxygen concentration in the cell environment. Research has confirmed the association of HIF-1a with an angiogenesis profile. Diagnostic monitoring of urine samples by fluorescence analysis methods allows detection of changes in fluorescence spectrum during disease as well as in response to therapy. These methods have the potential to improve diagnostic capture and to facilitate follow-up of patients.

bladder tumours, microRNAs, hypoxia-inducible factor, fluorescent urine examination
Klin urol 2019; 15 (3): 119 – 122

Ročník 2019  Témy časopisu Clinical urology 3 / 2019

Urological oncology

Jozef Marenčák
Monika Kmeťová Sivoňová, Peter Kaplán, Zuzana Tatarková, Jana Jurečeková, Henrieta Drobková, Róbert Dušenka, Mark Híveš, Ján Kliment sr.
Vladimíra Sobolová, Vincent Nagy

Funkcional urology

Ján Švihra, Magdaléna Hagovská, Ján Breza jr., Marek Vargovčák, Marek Brezovský
Roman Tomaškin

Case studies

Vincent Nagy, Andrej Böör, Ondřej Hes
Vladimír Bartoš, Barbora Šafeková, Dušan Pokorný
Patrik Kováč, Vincent Nagy, Ľubomír Lachváč, Zuzana Hríbiková
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CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

PROFESSIONAL EDITOR
prof. MUDr. Ján Švihra, PhD.

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Ing. Danica Paulenová
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SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum extent is 7 pages of text (font ARIAL or TIMES, font size 12, line spacing 1.5). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office.

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Structuring: introduction, clinical group and methods, results, discussion, conclusion, bibliography

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1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
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Write in 1st or 3rd person singular or plural (unify according the type of an article).
4. English translation: the title of the paper, summary, key words 5. Text
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6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses.
Citation means in general: the surname of the author (authors), title of the work, year of issuing, volume, pages.
Do not use "ét al.", but state all authors.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981:15-27.

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages.

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

All published papers are paid.

Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné