Téma: 

Has length of whole ischemic time (interval „symptom-balloon“) in patients with primary pci an impact on function of left ventricle?

Monika Jankajová, Martin Studenčan, Matej Moščovič, Radoslav Rosenberg

Introduction: Basic treatment in patients with ST segment elevation myocardial infarction (STEMI) is early reperfusion. The sooner the flow of closed artery is restored the lesser is the rate of heart attack, the better is the final function of the left ventricle LV (1). Aim: Ejection fraction of LV in patients with STEMI after primary coronary intervention (PCI) was analyzed depending on whole ischemic time (interval „symptom-balloon“). Methods: Retrospective analysis was used to analyze 147 consecutive patients with STEMI after primary PCI. Only patients without history of overcome heart attack were included. In 62 cases incomplete revascularization was performed by primary PCI, in 85 cases complete revascularization. Pearson´s correlation analysis, T-test and linear recessive analysis were used for statistical processing. Results: Mean time of interval „symptom-balloon“ was four hrs and fifty three min. Worse LVEF after procedure is associated with longer interval „symptom-balloon“ (β = -0.321, p < 0.001), incomplete revascularization (β = 0.194, p = 0.005) and need of intervention on RIA (β = -0.480, p < 0.001). Patients with complete revascularization had significantly better LVEF than those with incomplete revascularization (p = 0.045). Our analyses confirm the need of time loss minimizing of pre-hospitalization as well as hospitalization phase STEMI. Longer time intervals have significantly negative impact on left ventricle function in patients after primary PCL.

Ročník 2009  Témy časopisu Cardiology for practice 4 / 2009

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3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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