Vladimír Gomboš
The most common cause of chronic renal diseases (CHRD) and chronic renal failure (CHRF) is arterial hypertension (AH) and diabetes mellitus type 2 (DM2). Chronic renal insufficiency and chronic renal failure are potential risk factors (RF) of development and progression of cardiovascular (CV) diseases and related mortality. Multifactorial long-term mechanism of CV affliction is combination of traditional and non-traditional RF which have different risk potential in particular stages of CHRD. RF act independently or they potentiate themselves in combination with other RF and accompanying comorbidites and they are the cause of particular type and severity of CV risk. Patients with CHRD generally die more frequently due to CV disease than to renal disease. Life span of dialyzed patients in comparison of common population is significantly shorter. In 50 % of patients the cause of death are CV diseases. Despite therapeutic and diagnostic procedures in this group of patients there is not assumption of significant decrease of CV morbidity and mortality.