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Časopis Cardiology for practice – Článok Ace inhibitors have a class effect ‒ myth or reality?

Cardiology for practice

Reviewed, postgraduate scientific medical journal.
Period 4x per year
1336-3433
Free full text. The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Cardiology for practice
Cardiology for practice
Reviewed, postgraduate scientific medical journal.
Period 4x per year
Predplatné
Téma: 

Ace inhibitors have a class effect ‒ myth or reality?

Ján Murín, Jozef Bulas

Introduction of angiotensin converting enzyme inhibitors (ACEI) to treatment has brought a significant decrease of morbidity and mortality for several cardiovascular diseases. This benefit has been demonstrated by big randomized controlled trials (RCT) in which several medicament have been used. On the basis of differences between used molecules (medicaments), a discussion has been arisen if it is possible to extrapolate trial results with a specific molecule to other molecules (and thus also to other medicaments) inhibiting ACE and therefore to bring forward the argument of the effect of so-called class effect or to attribute the trial results to characteristic properties of the used medicament. Indubitable basis of the ACE inhibitors’ effect is so-called “class effect” even if there exist differences between particular molecules namely in pharmacokinetics (e.g. lipophilicity and penetration to tissues, bonds in tissues, half -time of the effect, metabolism and main mechanisms of excretion). According to the results of big RCTs in the approach of evidence-based medicine, molecules, with which these trials were performed, succeeded in the treatment of some clinical conditions, on the basis of reasoning that certain differences in the molecule properties besides the angiotensin convertase enzyme inhibition they might also provide a certain additive, more closely unspecified pharmacokinetic effect. Knowledge of the differences between particular molecules of ACE inhibitors should be taken into consideration in the choice of a suitable medicament for the particular patient.

Angiotensin converting enzyme inhibitors (ACEI), pharmacodynamics of ACE inhibitors, pharmacokinetics of ACE inhibitors, class effect of ACE inhibitors.
Kardiol. Prax 2012; 10 (4): 167-171

Ročník 2012  Témy časopisu Cardiology for practice 4 / 2012

Ján Murín, Jozef Bulas
Jana Klimasová, Ján Mazag
Juraj Dúbrava
Daniel Pella

Overview works

Ján Kyselovič

Juraj Dúbrava
Juraj Dúbrava
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Ideal candidate for primary prevention of sudden cardiac death with implantable cardioverter-defibrillator
Cardiac AL Amyloidosis In a 53-year-old Woman
Peripartum Cardiomyopathy
Postablation recurrence of paroxysmal tachycardia – what next?
Left ventricular assist device implantation as a bridge to candidacy (case report)
Pulmonary arteriovenous malformations
Echocardiography in aortic stenosis
STEMI: Possibilities of reperfusion treatment
STEMI management in Slovakia
Kawasaki disease from the cardiologist view
Sudden cardiac death: definition, epidemiology and reality
Patient management after a ICD discharge
Outpatient interventional procedures in cardiology – yes or no?
CHAIRMAN OF THE EDITORIAL BOARD
doc. MUDr. Oľga Jurkovičová, CSc.

CHIEF CONSULTANT
prof. MUDr. Robert Hatala, PhD., FESC

MEMBERS OF THE EDITORIAL BOARD
MUDr. Peter Dědič
MUDr. Juraj Dúbrava, PhD., FESC
MUDr. Viliam Fridrich, PhD.
doc. MUDr. Ján Kmec, PhD.
MUDr. Gabriela Kaliská, PhD., FESC
MUDr. Pavol Lesný
MUDr. Monika Kaldarárová, PhD.
MUDr. Peter Margitfalvi
prof. MUDr. Daniel Pella, PhD.
prof. MUDr. Iveta Šimková, CSc., FESC
MUDr. Viera Vršanská, CSc.

PROFESSIONAL EDITOR
MUDr. Juraj Dúbrava, PhD., FESC

EDITOR-IN-CHIEF
Ing. Danica Paulenová
e-mail: paulenova@amedi.sk

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SECTIONS

OVERVIEW PAPERS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum size is 8 pages (font size 12, line spacing 1.5) with maximum five pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with emphasis on its practical usage for cardiologists.

CASE STUDY 
Maximum extent is 7 pages. Structuring: summary, introduction, case study, discussion, conclusion, bibliography.

DIAGNOSTIC AND THERAPEUTICAL ALGORITHMS
Diagnosis and therapy processed into tables and schemes, with minimum text, with emphasis on conciseness and clarity.

MISCELLANEOUS
Reaction to overview articles, news in the field of diagnostics, therapy, trial results (maximum 3 pages), reports from professional events, abstracts from scientific work published abroad, not older than 1 year. Maximum extend is 1 page. Write the title of the paper in Slovak/Czech, authors, workplace, than title of the paper in English with full citation.

FROM BORDERLINE OF CARDIOLOGY
Inter sectional theme elaborated complexly, well-arranged, clear (extent up to 8 pages).


MANUSCRIPT ELABORATION

Write the paper on computer in any common text editor.
- write full length of lines (do not use ENTER at the end of a line)
- do not arrange text into columns
- do not do page make-up, put tables at the end of the paper
- distinguish precisely numbers 1, 0 and letters l, O
- use always parentheses ( )
- explain abbreviations always when first used


MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including academic titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
2. Summary - concise content summary in the extent maximum 10 lines (only at overview papers, case studies from borderline of cardiology). Write in 1st or 3rd person singular or plural (unify according the type of an article).
3. Key words - in the extent of 3-6 (just at overview papers, From borderline of cardiology).
4. English translation: paper title, summary, key words (only at overview papers, case studies and From borderline of cardiology)
5. Text
If you insert pictures into a document, send also their original files in "jpg" format, create graphs in Excel and send also their original files. If you send photo documentation via post office, please, send just high-class originals. Mark each original by a number, under which it is mentioned in the text. Write in 1st or 3rd person singular or plural (unify according the type of an article).
6. Bibliography
Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses. Use maximum 30 citations.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.

Do not use dots after first names in citations. Do not use colon but dot after names of authors. Use semi-colon after the year of publishing, colon is before pages. If an author is one, two or three - it is necessary to state all. If there are more than three authors it is necessary to write first three and "et all", in Slovak and Czech citations "a spol."

Due to publishing of autodidactic tests it is necessary to add 4 questions to your article and 4 answers with marking of one correct answer, e.g.:

In which patients, after overcoming of a thromboembolic cerebral or peripheral event, the least suitable catheter closure is foramen ovale patents:
a. a woman before planned pregnancy
b. paroxysmal fibrillation of the atrium
c. aneurysm of the atrium septum
d. origination of an event after cough

The editorial office reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are double reviewed.

All published papers are paid.

Due to practical focus of the journal we would like to ask you write the paper comprehensively, with emphasis on practical use of provided information in out-patient practice of cardiologists, internists and other professionals who deal with cardiovascular medicine.

Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 4x per year
1336-3433
Free full text. The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Cardiology for practice
Cardiology for practice
Reviewed, postgraduate scientific medical journal.
Period 4x per year
Predplatné