Monika Kaldarárová, Viera Vršanská, Tatiana Valkovičová, Peter Tittel, Iveta Šimková
Kawasaki disease is an acute febrile disease occurring in children - vasculitis of unknown etiology, dominantly affecting
coronary arteries. In case of late or inadequate treatment, severe and irreversible coronary aneurysms develop
in 20 – 30 % of cases. The presence of giant aneurysms is of high risk, especially from complete thrombotic
vessel closure or from the development of significant stenosis. These patients can any time develop acute coronary
syndrome and/or chronic ischemic impairments and myocardial dysfunction. Close follow-up and repeated re-evaluation
is therefore necessary. In patients after acute phase of Kawasaki disease with severe coronary affection the
most important is the continuous preventive combined antithrombotic and/or anticoagulation treatment. If needed,
surgical or percutaneous coronary intervention is performed.